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mouse models pten flox flox (Shanghai Model Organisms Center)

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Shanghai Model Organisms Center mouse models pten flox flox
Mouse Models Pten Flox Flox, supplied by Shanghai Model Organisms Center, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+model/fl+line+mouse+pten/pm42277975-43-2-16
Average 86 stars, based on 1 article reviews

mouse models pten flox flox - by Bioz Stars, 2026-09

86/100 stars

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Knock-In:

Article Title: Loss of Super-Enhancer-Regulated circRNA Nfix Induces Cardiac Regeneration After Myocardial Infarction in Adult Mice
Article Snippet: C57BL/6 mice and SD rats were purchased from Guangdong Medical Laboratory Animal Center. .. The Cas9 knock-in mouse model was obtained from Shanghai Model Organisms Center, Inc. ..

Article Title: BACE2‐Induced Aberrant Lymphatic Network Aggravates the Local Inflammation in Arteriovenous Fistulas With Hyperphosphatemia
Article Snippet: .. Lyve1 ‐Cre ER knock‐in mouse model was developed by Shanghai Model Organisms Center, Inc. as described previously. .. [ ] Wildtype (C57BL/6) mouse lines were purchased from Shanghai SLAC Laboratory Animal Co., Ltd. Pi16 ‐Cre ER , Prox1 ‐Cre ER , Vegfc em1Cflox , Vegfd em1Cflox , and Bace2 em1Cflox mouse lines (C57BL/6) were purchased from GemPharmatech Co., Ltd. Other mouse lines including, R26‐tdTomato (JAX: 007909) and R26‐DTA (JAX: 006331) mice lines were purchased from Shanghai Model Organisms Center, Inc. Genomic DNA from mice tail tissue was prepared by proteinase K lysed, isopropanol precipitated and 70% ethanol washed and then prepared for genotyping.

Article Title: BACE2-Induced Aberrant Lymphatic Network Aggravates the Local Inflammation in Arteriovenous Fistulas With Hyperphosphatemia.
Article Snippet: .. Mouse Generation and Breeding: Lyve1-CreER knock-in mouse model was developed by Shanghai Model Organisms Center, Inc. as described previously. .. [19] Wildtype (C57BL/6) mouse lines were purchased from Shanghai SLAC Laboratory Animal Co., Ltd. Pi16-CreER, Prox1-CreER, Vegfcem1Cflox, Vegfdem1Cflox, and Bace2em1Cflox mouse lines (C57BL/6) were purchased from GemPharmatech Co., Ltd. Other mouse lines including, R26-tdTomato (JAX: 007909) and R26-DTA (JAX: 006331) mice lines were purchased from Shanghai Model Organisms Center, Inc. Genomic DNA frommice tail tissue was prepared by proteinase K lysed, isopropanol precipitated and 70% ethanol washed and then prepared for genotyping.

Article Title: ACTR3 enhances the hyperproliferation of psoriatic keratinocytes by activating the TAK1-MK2-HSP27 pathway.
Article Snippet: doi:10.1111/febs.70558 Psoriasis is a chronic immune-mediated skin disorder characterised by abnormal keratinocyte proliferation and cutaneous inflammation.. ACTR3 (actin-associated protein 3) is significantly overexpressed in both cutaneous malignant tumours and psoriatic keratinocytes, and is recognised as a potential key nodal molecule linking tumours to inflammatory skin conditions.. Lysine 2-hydroxyisobutyrylation (Khib)—a critical post-translational modification—exerts regulatory effects on the pathogenesis of various diseases; however, its specific role in psoriasis pathogenesis remains elusive.

Article Title: Downregulation of lysine 2-hydroxyisobutyrylation of ErbB3 binding protein 1 at amino acid 210 promotes keratinocyte proliferation via induction of transcription initiation factor IA-mediated rRNA synthesis.
Article Snippet: .. The Pa2g4K210A knock-in mouse model was developed by the Shanghai Model Organisms Center (Shanghai, China). ..

CRISPR:

Article Title: Genetic variants in HELB contribute to premature ovarian insufficiency and early age of natural menopause.
Article Snippet: .. The mouse model was established on C57BL/6J genetic background using CRISPR/ Cas9 genome-editing technology by Shanghai Model Organisms Center, Inc. (China). ..

Generated:

Article Title: Testis-specific protein HSF5 is essential for proper chromatin organization and transcriptional reprogramming to drive pachynema progression
Article Snippet: .. The Hsf5 −/− mouse model was generated by Shanghai Model Organisms Center, Inc. (China). .. Briefly, Cas9 mRNA was transcribed in vitro using an mMESSAGE mMACHINE T7 Ultra Kit (Ambion, USA) according to the manufacturer’s instructions.